Does the UGREEN NASync DH4300 Plus support NVMe?
No. The UGREEN NASync DH4300 Plus has no internal M.2 slot, so it cannot take an NVMe SSD as a cache or a storage pool. Over its 1 × 2.5GbE that is barely a loss: a single CMR drive already saturates the link, and a cache only helps data you read repeatedly. If an NVMe cache or pool matters to you, choose a model with M.2 slots.
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Want to know whether the DH4300 Plus fits your actual storage plan? Open the NAS Builder with this model weighted.
Do you actually need NVMe on the DH4300 Plus?
An NVMe cache accelerates random I/O: the many small, scattered reads and writes you get when lots of users, a database or virtual machines all hit the array at once. It does almost nothing for the workload the DH4300 Plus is built for: sequential file transfers, device backups and everyday storage. On this model the 1 × 2.5GbE connection is the real ceiling, so a cache sitting in front of the drives would have no headroom to give: the network fills up long before the disks become the bottleneck.
Put the money where it moves the needle instead. The bigger win is capacity: larger CMR drives with the best CA$/TB, sized in the drive-count calculator. If you genuinely need a cache; a busy multi-user array, 10-gigabit networking, or a database/VM workload; that is simply a different class of NAS: an Intel model with M.2 slots and faster networking. Our SSD cache guide explains when a cache earns its place and when it does nothing, and drives by model lists the boxes that have the slots.
Drive policy: UGREEN locks no drive brand on the DH4300 Plus; its compatibility list is guidance, not a gate. The DH4300 Plus’s full compatibility rules.
Keep calculating
To see how much capacity is left after parity, the DH4300 Plus capacity calculator is preset to its 4 bays and RAID types. For the DH4300 Plus, the wider basics of choosing a drive are in the buying guides, and CMR versus SMR explains why SMR drives do not belong in a RAID array. Wondering what the DH4300 Plus can actually do: Plex, Immich, Docker, VMs? See what the DH4300 Plus can run.
Frequently asked questions
How many M.2 slots does the DH4300 Plus have?
None. No M.2 slots
Is an NVMe cache worth it in the DH4300 Plus?
Not possible: the DH4300 Plus has no M.2 slots. Over its 1 × 2.5GbE a cache would add little anyway, since a single drive already saturates the link.
Can I put third-party drives in the DH4300 Plus?
Yes. UGREEN locks no drive brand on the DH4300 Plus; its compatibility list is guidance, not a gate.

Devin Chua works out which drives, RAM and NVMe cache fit which NAS model at nasdrives.ca, and what the RAID choice means for usable capacity, checked against what is in stock on Amazon.ca.